Meaning
Analytical techniques evaluate a sample for all detectable substances rather than searching for a specific list of known chemicals. Non-targeted screening identifies unexpected migrants or impurities that might be present in a polymer due to raw material contamination or degradation.
Sample Analysis
High resolution mass spectrometry captures the data for every molecule that passes through the detector. This process does not require prior knowledge of the additives used in the plastic. Software then compares the observed masses against extensive databases to find matches for unknown peaks.
Risk Assessment
Identifying substances that were not intentionally added helps a manufacturer ensure that a part is safe for its intended use. Non-targeted screening reveals chemical signatures from process aids and cleaning agents that a standard test would miss. This discovery can lead to a better understanding of the total migration profile of the material.
Detection Strategy
Modern labs use this approach to map the entire chemical profile of a food contact material. If a new substance appears in the results, the lab can investigate the supply chain to find the source. This broad view allows for better control over the final product quality.
The results are often used to define the scope of future targeted testing.